Wayne State BME concentrations

  1. Injury biomechanics
  2. Biomaterials/tissue engineering
  3. Biomedical imaging
  4. Bioinstrumentation
  5. Computational systems biology
  6. Interdisciplinary

More information on select concentrations is below. 

Injury biomechanics

  • Goals of the impact-related research laboratories include developing new tests and methods to continuously reduce the severity and frequency of injuries.
  • We focus on understanding the mechanisms of injuries that are still difficult to explain.
  • By employing micromechanical, imaging, modeling and non-destructive techniques, the biological and mechanical factors that affect skeletal integrity can be investigated.
  • Expertise in computational modeling range from the tissue to the sub-cellular level.
  • Current research efforts include experimental and analytical analyses of the impact responses, injury tolerances and injury mechanisms of the human body from head to foot.
  • Using finite element modeling techniques, we have developed a human head model that is made up of more than 300,000 elements.
  • Each of these areas of research contributes to the ongoing development of a whole body human model.
  • Wayne State has a rich history in the area on sport injury biomechanics. The evaluation of headgear and research to provide support for the development of standards has long been a major role of the Sports Injury Biomechanics Laboratory.
  • Recent research has included the evaluation of boxing headgear and the comparison between male and female boxers.
  • New projects include the evaluation of mTBIin professional football, on field data collection of soccer heading and empirical testing of thoracic impacts.

Biomaterials/tissue engineering

  • Wayne State's biomaterials laboratories focus on the development and biocompatibility of novel biomimetic design for tissue regeneration.
  • Researchers specialize in novel biomaterials designs.
  • Tissue engineering involves the application of engineering principles, biological knowledge and materials technology to the study of and manipulating of living cells.
  • Wayne State's tissue engineering laboratories research tissue regeneration systems, including bone, peripheral nerves and adult stem cell expansion technologies.
  • Other major projects involve regenerating liver tissue, small/large diameter blood vessels and cardiac heart valves.
  • New and exciting applications involve the use of bioactive polymers and novel nanostructure materials.

Biomedical imaging

  • Magnetic resonance imaging holds great promise for investigating not only anatomical structures of the human body, but also the physiological process.
  • The Magnetic Resonance Research Facility has developed a number of important and exciting applications for this mode of imaging as they pertain to both clinical and basic science.
  • Sequence design, image reconstruction, image processing aid clinical applications. Among the areas that have been pioneered are: MR angiography, fast imaging, new construction methods, susceptibility weighted imaging and coronary artery imaging.
  • In the area of neuro-imaging, the focus has been on neuro-vascular related diseases. This includes the application of MRI for cerebral vasculature evaluation, vessel tracking, perfusion imaging and the use of susceptibility weighted imaging (SWI) to look for irregularities in the venous vasculature and for increases in brain iron content.
  • This has a clinical application in the areas of stroke, trauma, occult vascular disease and the study of angiogenesis in tumors. Another area of interest is cardiovascular imaging, where efforts are directed at creating 3D coronary artery imaging technology for MRI.