Tissue engineering is a multidisciplinary field that entails the application of engineering principles, biological knowledge and materials technology to the study and manipulation of living cells. This effort aims to achieve either repair or regeneration of damaged or diseased tissue or the reconstitution of tissue function ex vivo. The design and evaluation of biologically active materials is an integral component of this work. In the Tissue Engineering Laboratory, work is being conducted on liver regeneration systems, small and large diameter blood vessels, peripheral nerve conduits, and adult stem cell expansion technologies. In the area of biologically active materials, the laboratory has particular expertise in the design and application of bioactive polysaccharides as the structural components of engineered tissue systems.