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Professor, Engineering Technology, Electric-drive Vehicle Engineering Gene Liao

Professor, Engineering Technology, Electric-drive Vehicle Engineering Gene Liao

will be speaking on a panel on "Green Mobility Training Opportunities" at the Michigan Academy for...
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Apply for 2015-16 WSU Private Scholarships Now!
January 1 2015
Apply now for WSU private scholarships for the 2015-16 academic year. The submission deadline for the application and all required materials is March 31, 2015. Not all WSU Private Scholarships require submission of the Private Scholarship Application. If the Private Scholarship Application requirement is not indicated in the description of the scholarship, then only the submission of the Free Application for Federal Student Aid (FAFSA) is required. Complete your 2015-16 FAFSA by March 31, 2015 at fafsa.ed.gov. The annual FAFSA is available January 1 for the upcoming year.
College of Engineering Graduate Student Orientation Winter 2015
January 12 2015 at 10:00 AM
Danto Engineering Development Center Auditorium
Incoming engineering graduate students, join us for this very important day of introductions to Wayne State University and the College of Engineering. Orientation is strongly recommended for all new graduate students, especially international students. This is the first step on your path to success as a graduate student. Don't delay--RSVP by January 1st! Reminder: you may register for classes now! Please contact our advisors or the Graduate School with any specific questions. We look forward to seeing you this fall.
Nano@Wayne Seminar with Arun Anatharam & Korosh Torabi, Wayne State University
January 13 2015 at 2:30 PM
Welcome Center Auditorium
The Office of the Vice President for Research is pleased to host the next Nano@Wayne Seminar on Tuesday, Janurary 13, 2015 at 2:30 p.m. at Wayne State University's Welcome Center Auditorium. The guest presenters will be Arun Anatharam and Korosh Torabi, Wayne State University. Dr. Anatharam will present, "Molecular heterogeneity of secretory vesicles shapes the properties of neuroendocrine cell secretion," and Dr. Torabi will present,"Computational Studies of Motor Proteins." A reception will immediately follow in the Welcome Center Lobby. The seminar is free; registration is requested. Arun Anatharam Biography: He is a assistant professor of Biological Sciences at Wayne State Univeristy. He finised his postdoctoral fellow at University of Michigan in Biphysis and Cell Biology. He has been at the university about 3 years now.  Abstract: The chromaffin cell secretory response has been modeled extensively using biophysical methods, including measurements of changes in plasma membrane capacitance in stimulated cells. The models are consistent with seemingly interchangeable pools of readily releasable, slowly releasable and reserve vesicles. A major assumption has been that vesicles have the same biochemical constituents and that the fusion reaction and the rates of discharge of vesicle contents are uniform. This idea is challenged by our recent findings. Specifically, we discovered that chromaffin vesicles within the same cell can have functionally different isoforms of the key endogenous Ca2+ sensor Synaptotagmin (Syt). These isoforms (Syt-1 and Syt-7) confer different Ca2+ sensitivities to the vesicles in situ enabling them to respond differentially to depolarizing stimuli.  Using a powerful curvature-sensitive optical approach (polarized Total Internal Reflection Fluorescence Microscopy – pTIRFM) (Anantharam, et al., 2010), we also characterized detailed properties of individual fusion events. Based on these measurements, it is clear that fusion pores of vesicles with the different synaptotagmin isoforms have expansion rates that differ by greater than 10-fold. Fusion pores of vesicles with Syt-7 are often stabilized as a narrow neck for tens to hundreds of seconds, strongly slowing the discharge of lumenal proteins. Fusion pores of vesicles with Syt-1 invariably expand within seconds of fusion.  In the seminar, I will discuss a revised model of the chromaffin cell secretory response in light of these recent findings.  Korosh Torabi Biography: He is an assistant professor of Chemical Engineering and Materials Science at Wayne State University.He has served as postdoctoral fellow in the Department of Chemistry and the Non-equilibrium Energy Research Center at Northwestern University under the supervision of Professor George C. Schatz. Abstract:Inside any living cell a large variety of molecular machines are relentlessly at work. These motor proteins use adenosine triphosphate (ATP) as a fuel to carry out their biological functions. Different families of membrane integral proteins are constantly pumping ions across the membrane and against their chemical potential gradients. A variety of motor proteins are actively moving cargos around inside the cell. From medicine to nanotechnology, understanding these nanoscale machines is of importance to a wide range of scientific endeavors. Numerous experimental techniques such protein crystallography, kinetic measurements and various molecular spectroscopy methods have shown a great potential in elucidating the mechanochemistry of various motor proteins. None the less some important questions still remain beyond the rich of available experimental techniques. In this talk, I provide an overview of some computational approaches we are using in our quest for the missing pieces in the puzzle of some motor protein work cycles. I explain how some topological and structural analysis methods can potentially map out the allosteric communication pathways within a motor protein and predict the binding interactions at protein-protein interfaces. I also discuss some molecular simulation based techniques with promising outlooks on explaining motor protein structures and dynamics that are missing from experimental portfolios.  
Probability and Statistics Seminar
January 14 2015 at 2:00 PM
Faculty/Administration #1140 | Map 656 W. Kirby Detroit, MI 48202
Speaker:  Siqian Shen, University of Michigan, Ann Arbor Siqian Shen is an Assistant Professor of Industrial and Operations Engineering at the University of Michigan. She obtained a B.S. degree from Tsinghua University in China in 2007 and a Ph.D. from the University of Florida in Industrial and Systems Engineering in 2011. Her research interests are in mathematical optimization, particularly in stochastic programming, network optimization, and integer programming. Applications of her work include power system optimization, health care operations management, transportation networks, and cloud computing. She was named one of the two runners-up of the 2010 INFORMS Computing Society Best Student Paper award, was awarded the 1st Place of the 2012 IIE Pritsker Doctoral Dissertation Award, and was a recipient of 2012 IBM Smarter Planet Innovation Faculty Award. Title:  Chance-Constrained Surgery Planning Under Uncertain or Ambiguous Surgery Durations Abstract:  We consider surgery planning problems under uncertain surgery durations. We decide which operating rooms (ORs) to open, the allocation of surgeries to ORs, as well as the sequence and time to start each surgery. We formulate a binary integer programming model with individual and joint chance constraints to restrict the risk of having surgery delays and OR overtime, respectively. The chance-constrained program is reformulated as an integer program based on finite samples of the random surgery time. We further consider a distributionally robust problem variant by assuming ambiguous distributions of random surgery durations, for which we build a confidence set using statistical divergence functions. The robust variant restricts the maximum risk of surgery delay and overtime for any probability distribution function in the confidence set, and is equivalent to a chance-constrained program evaluated on an empirical probability function but with smaller risk tolerances. We compare different models and derive insights about surgery planning under data uncertainty and ambiguity using problem instances based on data from hospital-based surgery practice.
PAD Seminar - How to Write Your Personal Statement
January 15 2015 at 1:00 PM
5057 Woodward
The offices of the Vice President for Research, Provost, and Faculty Affairs (School of Medicine) are pleased to offer the Professional and Academic Development seminar series for WSU faculty, chairs & directors, postdoctoral trainees & graduate students, and administrators. Seminars are free, but registration is required. This seminar, How to Write Your Personal Statement, will take place Thursday, January 15, 2015, 1-2:30 p.m. at 5057 Woodward, 6th Floor, Conference Room A. The moderator will be Margaret Winters, Provost and Senior Vice President for Academic Affairs. Although PAD seminars will no longer be recorded due to low viewing activity, please see past seminar videos and handouts on the PAD website. If you have questions about this seminar series, please contact fgiblin@wayne.edu. We hope to see you at this informative PAD session!  
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