Haipeng Liu

Haipeng Liu

Assistant Professor, Chemical Engineering

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Haipeng Liu

Biography

2009 - 2013
Postdoctoral Associate, Department of Materials Science and Bioengineering
Department of Materials Science and Bioengineering, HHMI
Massachusetts Institute of Technology (Cambridge, MA).

2007 - 2009
Postdoctoral Associate, Department of Chemistry
Department of Physiology and Functional Genomics, Shands Cancer Center
University of Florida (Gainesville, FL)

Education

B.S. Chemical Engineering, Huazhong University of Science and Technology, Wuhan, China. 1998.
M.S. Polymer Chemistry and Physics, Huazhong University of Science and Technology, Wuhan, China. 2001.
Ph.D. Chemistry, Purdue University - West Lafayette. 2007.

Research Interests

Integrating approaches in synthetic chemistry and materials engineering for improving vaccines against autoimmune disorders, infectious diseases and cancer.

 

Research Projects

1. Engineering Albumin-hitchhiking vaccines for autoimmune diseases.

2. Designing multivalent molecular adjuvants (toll-like receptor agonists) for antigen presenting cells stimulation.

3. Engineering synthetic nanomaterials as antigen/adjuvant or drug carriers for subunit vaccine delivery.

Publications

1. Liu, H.; Zheng, Y. et. al., Structure-based programming of the immune response by synthetic albumin hitch-hiking molecular vaccines. Nature, under revision.

2. Xiong, X.*; Liu, H.*; Zhao, Z.; Altman, M.; Lopez-Colon, D.; Chang, L. J.; Liu, C.; Tan, W. DNA Aptamer-mediated Cell Targeting. Angewandte Chemie International Edition 2013, 52, 1472-1476.

3. Liu, H.; Kwong, B.; Irvine, D. J. Membrane Anchored Oligonucleotides for in vivo Tumor Cell Modification and Localized Cancer Immunotherapy. Angew. Chem. Int. Ed. Engl. 2011, 50, 7052-7055.

4. Kwong, B.; Liu, H.; Irvine, D. J. Induction of potent anti-tumor responses while eliminating systemic side effects via liposome-anchored combinatorial immunotherapy. Biomaterials. 2011, 32, 5134-5147.

5. Liu, H.; Zhu, Z.; Kang, H.; Tan, W. DNA Encoded Micelles: Synthesis, Micellar Properties and Size-dependent Cell Permeability, Chem. Eur. J., 2010, 16, 3791-3797.

6. Liu, H.; Ye, T.; Mao C. Fluorescent Carbon Nanoparticles Derived from Candle Soot. Angew. Chem. Int. Ed. 2007, 46, 6473-6475.

6. Liu, H.; Chen, Y.; He, Y.; Ribbe, A. E.; Mao C. Approaching The Limit: Can One DNA Oligonucleotide Assemble into Large Nanostructures? Angew. Chem. Int. Ed. 2006, 12, 1942-1945.